RECHARGE UNIVERSITY
RECHARGE
Health & Wellness
crohn's disease therapy
crohn's disease OVERVIEW
Crohn's disease is a chronic disease that causes inflammation in your digestive tract. It can affect any part of your digestive tract, which runs from your mouth to your anus. But it usually affects your small intestine and the beginning of your large intestine. Crohn's disease is an inflammatory bowel disease (IBD). Ulcerative colitis and microscopic colitis are other common types of IBD. The cause of Crohn's disease is unknown.
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THERAPY OVERVIEW
Even with all pharmacological advances in the treatment of CD, many patients still present a relapsing course. Some cases are impressively aggressive and mutilating. This situation usually requires surgical intervention and other measures to improve wound healing. Utilization of Hyperbaric Oxygen in patients with Crohn's Disease has increased in recent years. Hyperbaric Oxygen promotes increments in plasmatic partial pressures of O2, thus enhancing tissue levels of oxygenation. Tissue hyperoxia increases the healing processes as it leads to vasoconstriction and decreased edema and also stimulates angiogenesis and proliferation of fibroblasts and collagen. There are also some reports of increased bacteriostatic and bactericidal effects.
HBO acts directly in the inflammatory cascade and the effect of such therapy can be explained by reduced activity of nitric oxide synthase and inhibition of inflammatory cytokines. It is effective in suppressing the activity of COX-2 and the stimuli for the THF-alpha production. Vascular endothelial growth factor (VGEF) is significantly increased with HBO
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SCIENTIFIC BACKED RESULTS
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Crohn's disease and hyperbaric oxygen therapy
LE Iezzi, MR Feitosa, BA Medeiros, JC Aquino… - Acta Cirúrgica …, 2011 - SciELO Brasil
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Healing of severe perineal and cutaneous Crohn's disease with hyperbaric oxygen
CE Brady III, BJ Cooley, JC Davis - Gastroenterology, 1989 - Elsevier
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Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis
DA Rossignol - Medical gas research, 2012 - Springer
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effectiveness
Thirteen studies of Hyperbaric Oxygen therapy for people suffering with Crohn's disease were recently done along with 6 studies for ulcerative colitis. In all studies, participants had severe disease refractory to standard medical treatments, including corticosteroids, immunomodulators and anti-inflammatory medications. In patients with Crohn's disease, 31/40 (78%) had clinical improvements with Hyperbaric oxygen therapy, while all 39 patients with ulcerative colitis improved.
DA Rossignol - Medical gas research, 2012 - Springer
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HOW OFTEN
How often should you repeat this therapy? The crohn's disease therapy program at Recharge requires a once per week visit to the club for 90 minutes per session.
RESULTS
What are the results of this therapy? After approximately 6-8 weeks clients should see a noticeable improvement
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